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First thing is to check to make sure heat, lighting and other parameters are normal. If a heat mat is stuck on, or lighting timer isn't turning off at night, that could do it.
If it were me, I'd monitor for a week or two and if the behavior persists, I'd take it to the vet. Could be some illness/condition that's causing discomfort (the 'walking weird' seems relevant here, though that might be the human mind seeing clues that aren't there).
It could be that he just didn't want to be messed with yesterday, or that he misread something about your last interaction and is on high alert. Breeding season is starting up again, so it may be that he's just being affected by hormones (or whatever triggers seasonal variation in behavior).
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