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I don't really see any *genetic* reason preventing the hybridization aspect of such a project. I do, however, see the practical difficulty of establishing breeding lines without extensive inbreeding. I'm rather skeptical of the genetic health of non-wild-type snakes anyway (due to inbreeding for lines and the genetic bottleneck around the first individual to manifest the trait), and in the process of establishing these traits in different localities, you'll be setting up yet another genetic bottleneck and further reducing the genetic diversity present.
Of course, there are ways to minimize the problems, but it's an issue of scale: the sheer number of animals needed and breeding to be done to minimize genetic trouble would probably be financially unfeasible, and smaller scale operations could produce the right effects, but only with some loss of genetic health.
Henry
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