Universal antivenom being tested at Duke could change snake bite treatment worldwide - FaunaClassifieds
FaunaClassifieds  
 Sponsors   Breeders | Dealers |  Importers/Exporters | Caging | Feed | Supplies | Services | Events 
  Inside FaunaClassifieds  Product Reviews |  Classifieds!   | Photo Gallery   | Banner Advertising 
 
  YES! You can option out of the Google and InfoLinks ads! Click here!

Go Back   FaunaClassifieds > Reptile & Amphibian - General Discussion Forums > Herps In The News

Notices

Herps In The News Local or national articles where reptiles or amphibians have made it into the news media. Please cite sources.

Reply
 
Thread Tools Display Modes
Old 07-03-2022, 12:26 PM   #1
bcr229
Universal antivenom being tested at Duke could change snake bite treatment worldwide

https://www.newsobserver.com/news/lo...263070193.html
 
Old 07-03-2022, 01:14 PM   #2
Martin Nowak
Interesting study. Here is a link to the study parameters and the 8 U.S. academic medical center participants. The study began in August 2021, is seeking 100 patients, and expects to finish September 2022.

https://clinicaltrials.gov/ct2/show/NCT04996264

Press release by Ophirex, the sponsoring company - inventor of the snakebite oral pill. Fascinating approach.

https://www.ophirex.com/20220314-oph...-for-snakebite
 
Old 07-07-2022, 02:07 PM   #3
bcr229
This treatment won't be cheap. A 2018 study of Varespladib to treat coral snake venom in pigs - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265968/ - found an effective dosage of 1 mg per kg of patient body weight, so about 50 mg of Varespladib would be needed to treat an adult person.

Current pricing can be found from chemical supply stores. These are not drug makers, these stores sell to the makers, and of course there's going to be a ton of markup by the maker and then the retailer. Unless someone has an awesomely generous pharmacy/insurance plan or guaranteed low co-pays, I don't see a keeper being able to afford keeping a dose at home.

https://www.sigmaaldrich.com/US/en/p.../sigma/sml1100

https://www.adooq.com/varespladib-methyl.html
 
Old 07-12-2022, 03:29 PM   #4
JColt
I'm sure CroFab will find a way to make money off it also.
 
Old 07-12-2022, 10:44 PM   #5
nickolasanastasiou
Quote:
Originally Posted by bcr229 View Post
This treatment won't be cheap. A 2018 study of Varespladib to treat coral snake venom in pigs - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265968/ - found an effective dosage of 1 mg per kg of patient body weight, so about 50 mg of Varespladib would be needed to treat an adult person.

Current pricing can be found from chemical supply stores. These are not drug makers, these stores sell to the makers, and of course there's going to be a ton of markup by the maker and then the retailer. Unless someone has an awesomely generous pharmacy/insurance plan or guaranteed low co-pays, I don't see a keeper being able to afford keeping a dose at home.

https://www.sigmaaldrich.com/US/en/p.../sigma/sml1100

https://www.adooq.com/varespladib-methyl.html


Those are small-scale research samples at lower purity. They do not represent the cost of higher-purity API in a Drug Product manufactured at scale. It is completely disconnected. If you want to see another disconnected example (that might put one's mind at ease to a degree), look at a reference standard on Sigma for metformin hydrochloride (an inexpensive API in tablets commonly and inexpensively used as a first-line treatment for oral control of insulin resistance and Type-II diabetes mellitus) Mind you, I am not saying the drug will be inexpensive, but the pricing of research samples is not indicative of the cost of Drug Product due to undisclosed contributing factors in the background.
 

Join now to reply to this thread or open new ones for your questions & comments! FaunaClassifieds.com is the largest online community about Reptile & Amphibians, Snakes, Lizards and number one classifieds service with thousands of ads to look for. Registration is open to everyone and FREE. Click Here to Register!

 
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Similar Threads
Thread Thread Starter Forum Replies Last Post
Interesting article on bite treatment research Lucille Venomous Snakes Discussion Forum 1 05-17-2014 04:39 PM
best treatment for snake mites? grizlywinkleman Ball Pythons Discussion Forum 12 08-09-2011 01:32 PM
Tampa policeman gives literary treatment to gator bite report wcreptiles Herps In The News 1 11-06-2009 10:38 AM
Aquarium stocks up on antivenom for sea snake exhibit Clay Davenport Herps In The News 1 11-15-2005 09:40 AM
A VERY SCARY hot bite treatment in the EXTREME old guy Venomous Snakes Discussion Forum 7 02-21-2005 08:22 PM


All times are GMT -4. The time now is 11:27 AM.







Fauna Top Sites


Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2022, Jelsoft Enterprises Ltd.
Page generated in 0.04247689 seconds with 10 queries
Content copyrighted 2002-2022, FaunaClassifieds, LLC