Global Snakebite Envenomation and Antivenin Report - FaunaClassifieds
  Tired of those Google and InfoLink ads? Upgrade Your Membership!
  Inside FaunaClassifieds Ľ Photo Gallery  

Go Back   FaunaClassifieds > Reptile & Amphibian - General Discussion Forums > Herps In The News


Herps In The News Local or national articles where reptiles or amphibians have made it into the news media. Please cite sources.

Thread Tools Display Modes
Old 09-28-2023, 03:56 PM   #1
Martin Nowak
Global Snakebite Envenomation and Antivenin Report

"Exact numbers can be hard to determine, but globally itís estimated that as many as 2.7 million people are envenomed by snakes every year. Of these, up to 400,000 are permanently disabled, and estimates suggest that 81,000 to 138,000 die. Poorer nations suffer the greatest proportion of snake bites."

"The world produces less antivenom than it needs, and production quality varies. The cost to manufacture the remedy is more than most patients can afford, and anti-venom isnít exactly a profitable business, which deters its production. And those bitten often live in remote areas where they can't access antivenom quickly."

"Development is underway for a universal snake antivenom"
Quotes Source: "Today in Science - Scientific American". 9/27/2023

Full Report:
Old 09-29-2023, 06:10 PM   #2
I would assume a synthetic antivenin would cost more than the real thing to manufacture. And I don't understand how you could have a "universal" antivenin? So many enzymes in each of the different types of venom, that would be a tough endeavor.
Old 09-29-2023, 09:23 PM   #3
Martin Nowak
It would seem a tall order and complex undertaking to develop a synthetic universal antivenin. Even if one considered broad groupings such as "universal elapid" or "universal crotalid" and so forth. There are reports of successful bite treatment when species specific antivenin is unavailable but "closely related" species antivenin is available and used. I recall this among elapid envenomations.
It has been known for some years that CroFab is less effective on bites from C. helleri and C. oreganus. I don't know if these species' venom is used in production - suspect not. Here is a recent report (December 2022) indicating CroFab was not effective in treating a patient with C. helleri envenomation. Readers may also wish to look at the citations at the end of the article. Multiple reports of "how well CroFab worked on different species".
Old 09-30-2023, 11:02 AM   #4
We had a thread on the Ophirex universal treatment study last year. Fascinating stuff.
Old 09-30-2023, 11:28 AM   #5
Martin Nowak
Several years ago I was engaged to write a business plan for a VC start-up coral snake antivenin production facility. It quickly became apparent that such is enormously expensive for extremely few incidences and the notion was terminated. Plus, coral snake envenomation can be treated without antivenin.

Here is the Ophirex-BRAVO updated clinical trial link. Note that the Phase 2 trial reports completion in June 2023 with 96 of desired 110 participants. Will be interesting to read their results when available.

Here is the home page for Ophirex:

Here is the January 2023 Series B funding round of $37 million:

Join now to reply to this thread or open new ones for your questions & comments! is the largest online community about Reptile & Amphibians, Snakes, Lizards and number one classifieds service with thousands of ads to look for. Registration is open to everyone and FREE. Click Here to Register!


Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Similar Threads
Thread Thread Starter Forum Replies Last Post
Antivenin Package Inserts wamartin67 Venomous Snakes 0 06-04-2012 04:57 AM
Self-envenomation GinoInDaBronx Venomous Snakes 7 04-11-2006 01:21 AM
Cro Fab antivenin Rattlesnake Venomous Snakes Discussion Forum 6 04-02-2006 01:18 AM
Zoo's Antivenin Saves Snakebite Victim Clay Davenport Herps In The News 2 02-09-2005 12:35 AM
Agkistrodon self envenomation gila7150 Venomous Snakes Discussion Forum 4 08-03-2004 10:48 AM

All times are GMT -4. The time now is 07:05 AM.

Fauna Top Sites

Powered by vBulletin® Version
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Page generated in 0.06251907 seconds with 10 queries
Content copyrighted ©2002-2022, FaunaClassifieds, LLC