As an HVAC pro, you're asking a lot deeper question than you realize.. Flexwatt probably doesn't put off the required btuhs to heat the room, AND it's not rated to be installed under/in a floor.
There is a heat cable you can install underneath tile that would do a much better job. However, you need to keep in mind that you have to insulate underneath the heat source to force the heat to go toward the direction you want (up), as heat doesn't naturally rise, it transfers. (Hot air rises, not heat).
Some questions:
What type of insulation does it have? 10'x12' x how tall? What's the outside temperature? Does it have a window or two? What is the u-value of the window? Is the door an exterior door? Do you use ventilation? Is there a crawl space, or air passage underneath the shed, or is it a slab on grade?
What I'm getting at, is that you need an accurate load calculation that takes into account the tightness/leakiness of the shed, the window(s), ventilation, r-value and type of insulation, etc. From that, one can determine the required BTUh's to maintain a set temperature.
Based on the size of 10x12, it seems like you have a leaky structure. Find and seal the leaks. Typically, if insulated with foam board (most recommended), that size should easily be heated with a 1000W heater. This is speaking from the experience of dealing with -35 deg. outside temps here...
One more thing... Once you can determine the proper amount of BTUh's required to heat the structure to 80 deg. (or whichever temp you're shooting for), you can determine how many watts of heat are needed. There are 3.412 BTUh per Watt of electric heat, so a 1000W heater will put out 3,412 BTUh. 1500W will put out 5,118 BTUh.
For your 11" flexwatt question, how many watts per foot is it? I'm thinking it's 10W/ft. Rounding the numbers, if you have 50' of 11" flexwatt, it should put off 500W. Will that heat the shed? Probably not. Again, I'd recommend that you find the heat leaks and stop them. (Fiberglass insulation is the worst possible insulation one could use to actually insulate with)