romad119
Member
I ahve noticed that my veiled somedays has swelling around teh eye sockets. It looks loose and fatty. Then the next day it will be gone, etc. Is this related to hydration levels?
Chris Anderson said:With chameleons, its more often too much vitamin A than too little. If this is an abnormal swelling and not just cleaning the eye, my feeling is it would probably be some type of infection or edema from over supplementation. What is your supplementation like and gutloading like? Any pics?
Chris
Chris Anderson said:
Wendy,
You really need to cite your source if you are quoting someones research like that.
According to Dr. Lopez, with over supplementation of vit A in chameleons, the liver starts to store the excess. At a certain point, it cannot store anymore and it can take weeks or months before normal levels are restored. When this happens, the liver becomes swollen and a sign is actually hypercalcemia (too much calcium in the blood, mobilized from the bones, a type of MBD). Edema then occurs (especially in the face and chin). Edema can often show up as swelling at the basally in the eye turrets. You can read up about much of this here: http://www.chameleonjournals.com/vet/index.php?show=5.Vitamin.A.html
I would agree with the statement that it is important to talk to a vet.
Chris
Chris Anderson said:Wendy,
I'd like to note that in no way does your source indicate that Vitamin A over supplementation does not effect the eyes as you stated in your post. Ferguson (2004) provides aditional information regarding his research with vitamin A in chameleons: "A deficiency of the fat-soluble vitamin A (retinol or retinyl-esters) retards growth significantly and causes several other pathological symptoms. These include eye closure or sensitivity, tail-tip necrosis, extreme spinal or tail flexure, loss of muscular coordination, hemipenal impaction, failure to undergo egg production, and metabolic bone disease in combination with there other symptoms (Ferguson et al. 1996)."
Chris
codyremmyloo said:I have never seen an article that said too much vitamin A caused eye problems only that too much vitamin A causes other problems, in an overdose of vitamin A the eyes are not mentioned as being affected.
So I should have worded it that way
Bringerofdoom said:Go figure, people who know nothing about nothing, dont bother to properly research stuff.
and what you said was still wrong. no wonder why chris tells you to stop telling people things. its not information, but misinformation.
HYPERVITAMINOSIS (excessive vitamin A)
Vitamin A
Excess vitamin A supplementation may interfere with the metabolism of vitamin D3, resulting in metabolic bone disease. Excess vitamin A supplementation may also lead to organ toxicity (Kidney, Liver).
And if we sidestep the provitamins and give preformed vitamin A it has to be better, right? Well, as Andy pointed out, vitamin A can be VERY toxic. As we give more provitamins (carotenoids), the conversion to retinol slows down and diminishes problems. But, if we give PREFORMED A it bypasses the barriers and barges in unabated. No problem, the liver will store it. What happens when the liver is full? A single dose can fill all available space in the liver. In most animals, it takes WEEKS for the liver to get back to normal concentrations of vitamin A after being at maximum capacity once all vit A has been excluded from the diet. Humans may take 6 months! When the liver is full, the incoming retinol with the "escorts" get really pissed. Their only job in life, getting to the liver, has been blocked. They have no choice but to go on a systemic rampage. While retinol released from the liver with the binding proteins can enter cells, the retinol with the chylomicrons (escorts) becomes toxic. One of the many signs of this is HYPERcalcemia. That's right, too much calcium in the blood. Where does the calcium come from? It is mobilized from the bones. The cham now has a type of metabolic bone disease. The liver is swollen, edema develops, especially in the face/chin region. The kidneys are damaged or destroyed. The cham becomes anemic. Some of this is reversible, some is permanent and can be fatal quickly
Bringerofdoom said:thats from your page
thats from chris's page samething, but the page chris links to bothers to go in depth about it. unlike your page that brielfy talks about it.