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Treatment of Cryptosporidium in leos.

I

Intense Herpetoculture

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I found this interesting abstract.
Thanks
Justyn

Hyperimmune bovine colostrum treatment of moribund Leopard geckos (Eublepharis macularius) infected with Cryptosporidium sp.

Graczyk TK, Cranfield MR, Bostwick EF.

Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA. [email protected]

Therapy based on the protective passive immunity of hyperimmune bovine colostrum (HBC) was applied to 12 moribund Leopard geckos (Eublepharis macularius) infected with Cryptosporidium sp. The geckos were lethargic and moderately to severely emaciated, weighing on average 36% of the baseline body weight value. Seven gastric HBC treatments at 1-week intervals each decreased the relative output of Cryptosporidium sp. oocysts and the prevalence of oocyst-positive fecal specimens. Histologically, after 8 weeks of therapy, seven out of 12 geckos had only single developmental stages of Cryptosporidium sp. in the intestinal epithelium, and three, one and one geckos had low, moderate and high numbers, respectively, of the pathogen developmental stages. The HBC therapy was efficacious in decreasing the parasite load in moribund geckos. Morphometric and immunologic analysis of Cryptosporidium sp. oocyst isolates originating from Leopard geckos (E. macularius) demonstrated differences between gecko-derived oocyst isolates and isolates of C. serpentis recovered from snakes.
 
That was interesting, complicated but interesting nonetheless.

Is there more or was that the extent of the report?

Do you know if the study they did on snakes is available?
 
I'll see if I can find out anything with the study on snakes. I guess I need to obtain a copy of this article and see what the details are.

wilomn said:
That was interesting, complicated but interesting nonetheless.

Is there more or was that the extent of the report?

Do you know if the study they did on snakes is available?
Click to expand...
 
Interresting, I hope that they expand that study. May lead to a "cure" for crypto. Wes, as to your question, I don't read that article as saying they did a seperate study on snakes, just that they did a comparative study on the Cryptosporidium sp, and that they are different in snakes ie. C. serpentis than in the analyzed Geckos. Which isn't suprising. I could be wrong in my interpretation, hopefully intense herpetoculture can find out more info.
 
I wondered about that myself but if there's a chance that there has been a study done with snakes I'd sure like to know. A close friend of mine lost his entire greyband collection to crypto a few years ago and that really hurt, he had some gorgous snakes.
 
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